Retinoic Acid Receptor, alpha (RARA) (Middle Region) Peptid
RARA
Reaktivität: Human
Wirt: Synthetic
BP, WB
Produktnummer ABIN982661
Kurzübersicht für Retinoic Acid Receptor, alpha (RARA) (Middle Region) Peptid (ABIN982661)
Target
Retinoic Acid Receptor alpha (RARA)
(Retinoic Acid Receptor, alpha (RARA))
Spezies
Human
Quelle
Synthetic
Applikation
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- Middle Region
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Produktmerkmale
- This is a synthetic peptide designed for use in combination with anti-RARA antibody (Catalog #: P100861_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Aufreinigung
- Purified
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Retinoic Acid Receptor, alpha (RARA) peptide
RARA Reaktivität: Human, Maus, Rind (Kuh), Hund, Ratte Wirt: Synthetic BP, Imm
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Applikationshinweise
- Each Investigator should determine their own optimal working dilution for specific applications.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Konzentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handhabung
- Avoid repeated freeze-thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Retinoic Acid Receptor alpha (RARA) (Retinoic Acid Receptor, alpha (RARA))
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Hintergrund
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Retinoid signaling is transduced by 2 families of nuclear receptors, retinoic acid receptor (RAR) and retinoid X receptor, which form RXR/RAR heterodimers. In the absence of ligand, DNA-bound RXR/RARA represses transcription by recruiting the corepressors NCOR1, SMRT, and histone deacetylase. When ligand binds to the complex, it induces a conformational change allowing the recruitment of coactivators, histone acetyltransferases, and the basic transcription machinery.
Alias Symbols: NR1B1, RAR
Protein Interaction Partner: NCOR1,NCOR2,ANP32A,BTG1,CDK7,KDM5A,MED6,NCOA1,NCOA2,NCOA3,PARP1,PRMT2,TNFRSF10B,BAG1,BTG1,CCND3,CDK7,CNOT1,COPS2,ESR1,FOXO1,GADD45G,GATA2,IRX4,ITGB1BP2,KAT2B,KDM5A,KLF5,MECR,MED1,MED6,NCOA1,NCOA3,NCOA6,NCOR1,NCOR2,NKX2-1,NPAS2,NR0B2,NR1H2,NR1H3,NR2E3,NRBF2,NRIP1,NRIP2,NSD1,PARP1,PML,PNRC2,POU2F1,PRDX6,PRKCA,RXRA,RXRB,RXRG,SNW1,SP1,SPEN,STAT5B,TADA3,TRIM24,TRIP4,UBE3A,ZBTB16,ARNTL,BAG1,CCND3,CLOCK,GADD45A,GADD45G,Gadd45b,HDAC3,HDAC4,IRX4,JUB,KAT2B,KDM5A,LIMD1,MECR,NCOA2,NCOA6,NCOR1,NCOR2,NKX2-1,NPAS2,NR0B2,NR2E3,NR4A2,NRBF2,NRIP1,Nr0b2,Nsd1,PML,POU2F1,RARA,RXRA,RXRB,RXRG,SKI,SP1,SRC,TADA3,TDG,TRIM24,TRIP4,WTIP,ZBTB16
Protein Size: 462 -
Molekulargewicht
- 51 kDa
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Gen-ID
- 5914
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NCBI Accession
- NM_000964, NP_000955
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UniProt
- P10276
Target
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